- Action for M.E. - the largest patient organisation, for adults and young people with M.E.
- M.E. Association - another national organisation, now semi-dormant.
- Association of Young People with M.E. - support for people aged 5-25 as well as their friends and families.
- 25 percent M.E. Group - specifically for those severely affected by M.E.
- Tymes Trust - The Young M.E. Sufferers Trust.
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